Ibogaine Treatment for Depression
A structured, medically supervised evaluation and treatment protocol for people living with depression that has not responded to other approaches, at IBTA in Paulinia, Brazil.
For many people living with depression, especially treatment-resistant depression, standard options — medication, therapy, and combinations of both — do not bring adequate relief, even after years of trying. That experience of exhausting the conventional options is often what leads someone to research ibogaine as an alternative. It is not a decision to take lightly, and it should always involve a thorough clinical evaluation.
If you are in emotional crisis or having thoughts of suicide, seek immediate help. While in Brazil, call 192 (SAMU, Brazil's emergency medical service) or go to the nearest emergency room. If you are in the United States, the 988 Suicide & Crisis Lifeline is available by call or text; if you are elsewhere, please contact your local emergency services or a crisis line in your country.
4 days, from admission to clinical discharge
A structured Monday-to-Thursday protocol, with a single supervised overnight stay in a monitored hospital environment.
Admission, exams and screening
Full check-up and first dose
- Welcome, medical history and documentation
- Blood count, liver enzymes (AST/ALT) and ECG
- Clinical evaluation
- First dose (test dose)
Therapeutic integration and high dose
Supervised overnight clinical stay
- Integrative therapy session
- Individual session with the therapeutic team
- Main Reset dose
- Overnight clinical stay with monitoring
Additional dose and integration
Return for therapeutic integration
- Monitoring of clinical progress
- Additional dose of ibogaine
- Integration of the experience
- Multidisciplinary follow-up
Closing and family guidance
Closing meetings
- Closing meeting with patients
- Family guidance meeting
- Guidance on medications and herbal supplements
- Clinical discharge and continuity plan
Care team: psychiatrists, psychologists/psychoanalysts, specialized therapists, 24h hospital nursing staff, and holistic therapists.
Safety
The IBTA protocol combines assisted ibogaine administration with clinical and psychological support, inside a structured safety environment. Treatment is not a replacement for psychiatric care, and patients are encouraged to keep their psychiatrist or therapist informed throughout the process, including afterward. There is no promise of a cure.
Exams and evaluation
- — Electrocardiogram (ECG) before administration
- — Complete blood count
- — AST and ALT liver function tests
- — Consent and commitment assessment
- — Psychiatric history and medication review
Required preparation
- — Four days without use of chemical substances (subject to case review)
- — Alcohol abstinence for the period defined during screening
- — Disclosure of all medications and supplements currently in use
- — Arranging a companion and lodging, when applicable
24h ambulance support integrated with a network of more than 40 hospitals and emergency rooms in the Paulínia region.
Contraindications
Severe psychiatric conditions
Schizophrenia, severe uncontrolled psychosis, or a history of psychotic episodes require exclusion or specialized evaluation.
Cardiovascular disease
Heart failure, arrhythmias, a recent heart attack, and other cardiac conditions may rule out treatment; each case is reviewed individually.
Hepatic or renal impairment
Cirrhosis, severe hepatic or renal insufficiency, and dialysis require rigorous medical evaluation.
Patients undergoing cancer treatment
Ongoing oncological treatment requires individual evaluation and may rule out the protocol; each case is reviewed individually.
Does ibogaine have side effects?
Ibogaine's side effects are most noticeable during Reset Day. Their intensity and combination vary from patient to patient.
Individual manifestation: some of these effects may occur, while other patients may not experience any of them. Even without noticeable symptoms, ibogaine's neurological effects continue to take place.
Reset
Effects are most noticeable during the main dose
Variable
Each patient responds individually
Team
Clinical supervision throughout the process
Our facilities
Hospital environment, therapy rooms, and welcoming spaces in Paulínia, São Paulo State, Brazil.
4.5 out of 5 stars on Google Maps
“I had deep depression, undergoing advanced and expensive treatments. I had already tried the best that international medical technology offers, without success. Ibogaine gave me my life... I was reborn the day I said goodbye to the IBTA team.”
Frequently asked questions
There is no guaranteed cure, and results vary from patient to patient. Treatment is intended to be part of a broader care plan, not a replacement for psychiatric follow-up.
Many patients researching this treatment have already tried standard options without adequate relief, but the evaluation is individual regardless of how long someone has been in treatment.
The core protocol is 4 days, but international patients should plan additional time around travel and post-treatment monitoring; our team provides specific guidance once an evaluation is scheduled.
Each case is evaluated individually, including current medications. The clinical team reviews this as part of screening to determine eligibility and any necessary adjustments.
Take the first step
Talk to our team and find out if treatment is right for you.
Book an evaluation on WhatsApp (+55 19 97107-5864)We'll ask for your name, WhatsApp/phone number, and whether treatment is for you or a family member.